经皮椎体成形术治疗老年骨质疏松性脊柱骨折的应用效果观察(1)
[摘要]目的 探讨经皮椎体成形术治疗老年骨质疏松性脊柱骨折的应用效果。方法 筛选我科2015年6月～2016年12月收治的100例老年骨质疏松性脊柱骨折患者，按照随机数字表法将其分成保守组与手术组，每组各50例。保守组应用保守治疗，手术组应用经皮椎体成形术治疗，比较两组治疗后的临床效果、疼痛程度以及骨密度。结果 手术组治疗后的总有效率为92.00%，高于保守组(78.00%)，差异有统计学意义(P<0.05)；两组治疗后的VAS评分均低于治疗前，且手术组低于保守组，差异均有统计学意义(P<0.05)；手术组治疗后24、48周的骨密度均大于保守组，差异有统计学意义(P<0.05)。结论 经皮椎体成形术治疗老年骨质疏松性脊柱骨折的应用效果理想，患者疼痛明显减轻，骨密度明显改善，值得临床推行与应用。
[关键词]老年；骨质疏松性脊柱骨折；经皮椎体成形术；保守治疗
[中图分类号] R687.3 [文献标识码] A [文章编号] 1674-4721(2018)7(a)-0095-03
[Abstract]Objective To investigate the effect of percutaneous vertebroplasty on elderly osteoporotic spinal fractures.Methods A total of 100 elderly patients with osteoporotic spinal fractures admitted to our department from June 2015 to December 2016 were divided into conservative group and surgical group according to a random number table method，50 patients in each group.In the conservative group，conservative treatment was used，while in the latter，percutaneous vertebroplasty was performed.The clinical efficacy，pain degree，and bone mineral density (BMD) were compared between the two groups after treatment.Results The total effectiveness rate after treatment in the surgical group was 92.00%，higher than that in the conservative group accounting for 78.00% with a statistical difference (P<0.05).The visual analogue scale (VAS) scores after treatment in both groups were lower than before treatment，and VAS score in the surgical group was lower compared with that in the conservative group with a significant difference (P<0.05).The BMD in the surgical group 24 and 48 week after treatment was greater than that in the conservative group with statistical significance (P<0.05).Conclusion Percutaneous vertebroplasty in the treatment of osteoporotic spinal fractures in the elderly can obtain a favorable effect by effectively relieving pain and improving BMD，which is worthy of clinical application and promotion.
[Key words]Elderly；Osteoporotic spine fractures；Percutaneous vertebroplasty；Conservative treatment
老年骨質疏松性脊柱骨折是临床上一种常见的骨折类型，因骨质疏松症而发病，主要表现为压缩性骨折，病变部位常伴有疼痛，随着病情的发展，患者的生活质量将受到严重影响[1]。在我国人口老龄化现象日趋形成的过程中，老年骨质疏松性脊柱骨折患者人数急剧增加，必须引起高度重视，积极给予治疗[2]。基于此，本研究为探讨经皮椎体成形术治疗老年骨质疏松性脊柱骨折的应用效果，筛选我科收治的患者的临床资料展开回顾性分析，并比较保守治疗与经皮椎体成形术治疗的差异性，现报道如下。
1资料与方法
1.1一般资料
筛选我科2015年6月～2016年12月收治的100例老年骨质疏松性脊柱骨折患者，均经X线、CT等检查确诊，符合临床诊断标准，均为压缩性骨折，患者有明显的腰背部疼痛症状，按照随机数字表法将其分成保守组与手术组，每组各50例。保守组男27例，女23例；年龄65～90岁，平均(72.5±7.1)岁；病程2 h～82 d，平均(11.5±3.3)d；致伤因素：跌伤34例，扭伤11例，不明原因5例；骨折部位：胸椎段22例，腰椎段28例。手术组男26例，女24例；年龄65～91岁，平均(72.2±7.0)岁；病程2 h～82 d，平均(11.9±3.1)d；致伤因素：跌伤33例，扭伤12例，不明原因5例；骨折部位：胸椎段22例，腰椎段28例。两组的性别、年龄、病程、致伤因素以及骨折部位等一般资料比较，差异无统计学意义(P>0.05)，具有可比性。所有患者均对本研究知情并同意，本研究经医院医学伦理委员会审核批准。, 百拇医药(王自刚 盛文辉)
[关键词]老年；骨质疏松性脊柱骨折；经皮椎体成形术；保守治疗
[中图分类号] R687.3 [文献标识码] A [文章编号] 1674-4721(2018)7(a)-0095-03
[Abstract]Objective To investigate the effect of percutaneous vertebroplasty on elderly osteoporotic spinal fractures.Methods A total of 100 elderly patients with osteoporotic spinal fractures admitted to our department from June 2015 to December 2016 were divided into conservative group and surgical group according to a random number table method，50 patients in each group.In the conservative group，conservative treatment was used，while in the latter，percutaneous vertebroplasty was performed.The clinical efficacy，pain degree，and bone mineral density (BMD) were compared between the two groups after treatment.Results The total effectiveness rate after treatment in the surgical group was 92.00%，higher than that in the conservative group accounting for 78.00% with a statistical difference (P<0.05).The visual analogue scale (VAS) scores after treatment in both groups were lower than before treatment，and VAS score in the surgical group was lower compared with that in the conservative group with a significant difference (P<0.05).The BMD in the surgical group 24 and 48 week after treatment was greater than that in the conservative group with statistical significance (P<0.05).Conclusion Percutaneous vertebroplasty in the treatment of osteoporotic spinal fractures in the elderly can obtain a favorable effect by effectively relieving pain and improving BMD，which is worthy of clinical application and promotion.
[Key words]Elderly；Osteoporotic spine fractures；Percutaneous vertebroplasty；Conservative treatment
老年骨質疏松性脊柱骨折是临床上一种常见的骨折类型，因骨质疏松症而发病，主要表现为压缩性骨折，病变部位常伴有疼痛，随着病情的发展，患者的生活质量将受到严重影响[1]。在我国人口老龄化现象日趋形成的过程中，老年骨质疏松性脊柱骨折患者人数急剧增加，必须引起高度重视，积极给予治疗[2]。基于此，本研究为探讨经皮椎体成形术治疗老年骨质疏松性脊柱骨折的应用效果，筛选我科收治的患者的临床资料展开回顾性分析，并比较保守治疗与经皮椎体成形术治疗的差异性，现报道如下。
1资料与方法
1.1一般资料
筛选我科2015年6月～2016年12月收治的100例老年骨质疏松性脊柱骨折患者，均经X线、CT等检查确诊，符合临床诊断标准，均为压缩性骨折，患者有明显的腰背部疼痛症状，按照随机数字表法将其分成保守组与手术组，每组各50例。保守组男27例，女23例；年龄65～90岁，平均(72.5±7.1)岁；病程2 h～82 d，平均(11.5±3.3)d；致伤因素：跌伤34例，扭伤11例，不明原因5例；骨折部位：胸椎段22例，腰椎段28例。手术组男26例，女24例；年龄65～91岁，平均(72.2±7.0)岁；病程2 h～82 d，平均(11.9±3.1)d；致伤因素：跌伤33例，扭伤12例，不明原因5例；骨折部位：胸椎段22例，腰椎段28例。两组的性别、年龄、病程、致伤因素以及骨折部位等一般资料比较，差异无统计学意义(P>0.05)，具有可比性。所有患者均对本研究知情并同意，本研究经医院医学伦理委员会审核批准。, 百拇医药(王自刚 盛文辉)